Homology of cryptic plasmid of Neisseria gonorrhoeae with plasmids from Neisseria meningitidis and Neisseria lactamica.

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Homology of cryptic plasmid of Neisseria gonorrhoeae with plasmids from Neisseria meningitidis and Neisseria lactamica.

DNA probe hybridisation was used to examine the relation between the cryptic plasmid from Neisseria gonorrhoeae and plasmids carried by pharyngeal isolates of Neisseria meningitidis and Neisseria lactamica. The complete gonococcal cryptic plasmid and HinfI derived digestion fragments subcloned into Escherichia coli were used to probe Southern blots of plasmid extracts. Homology was found to a p...

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Interaction of complement with Neisseria meningitidis and Neisseria gonorrhoeae.

The importance of the complement system in host defense against systemic infection caused by neisseriae is emphasized by a number of clinical observations documenting the importance of antibody-dependent, complement-mediated serum bactericidal activity in protection from systemic meningococcal disease (17) and the well-recognized association between the resistance of gonococci to complement-dep...

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Conjugative Plasmids of Neisseria gonorrhoeae

Many clinical isolates of the human pathogen Neisseria gonorrhoeae contain conjugative plasmids. The host range of these plasmids is limited to Neisseria species, but presence of a tetracycline (tetM) determinant inserted in several of these plasmids is an important cause of the rapid spread of tetracycline resistance. Previously plasmids with different backbones (Dutch and American type backbo...

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Tn916-generated, lipooligosaccharide mutants of Neisseria meningitidis and Neisseria gonorrhoeae.

A library of Tn916-generated, tetracycline-resistant (Tc) mutants of the group B Neisseri meningitidis strain NMB was screened by using monoclonal antibodies (MAbs) that recognize structural differences in neisserial lipooligosaccharide (LOS). The LOS of parental strain NMB had a relative molecular mass of 4.5 kDa, reacted with MAbs 3F11 and 6B4 but not with MAb 4C4 or 6E4, and contained a lact...

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Plasmids of Neisseria gonorrhoeae and other Neisseria species.

a These species were shown to carry plasmids of various sizes which hybridized with probes made from the 2.6-MDa plasmid. b Related plasmids are found in the genus Haemophilus (4). Identical plasmids are found in clinical isolates of K. denitrificans and Eikenella corrodens (24). d Related plasmids are found in enteric bacteria and Eikenella corrodens

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1986

ISSN: 0021-9746

DOI: 10.1136/jcp.39.10.1119